Description

4-Bromo-2-Propionylthiophene is a high-purity brominated thiophene derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a bromine substituent and a propionyl group on the thiophene ring, makes it an essential intermediate for constructing complex heterocyclic systems. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of new generation pesticides and herbicides, leveraging the thiophene scaffold for bioactivity.
• Material Science Research: Serves as a monomer or functional unit in the creation of conductive polymers, organic semiconductors, and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-organic catalysis and coordination chemistry.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Acts as a high-value intermediate in custom synthesis and contract manufacturing for specialty chemicals.

Basic Information

Product Name	4-Bromo-2-Propionylthiophene
CAS No.	36155-78-9
Molecular Formula	C7H7BrOS
Molecular Weight	219.10 g/mol
Synonyms	1-(4-Bromo-2-thienyl)-1-propanone; 4-Bromo-2-propionylthiophene; 4-Bromo-2-propanoylfuran; 4-Bromo-2-thienyl ethyl ketone; 2-Propanone, 1-(4-bromo-2-thienyl)-; 4-Bromo-2-acetylthiophene (common misnomer, verify structure); 4-Bromo-thiophene-2-propionic acid ketone
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-Propionylthiophene is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.