Description

1-(2,5-Difluorophenyl)-4,4,4-Trifluorobutane-1,3-Dione is a high-purity fluorinated diketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both difluorophenyl and trifluoromethyl groups, makes it a versatile precursor for creating complex molecules with tailored electronic and physical properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs), where fluorine atoms are used to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides that benefit from the enhanced lipophilicity and stability imparted by fluorine.
• Ligand and Catalyst Development: Serves as a precursor for β-diketonate ligands, which are used to form metal complexes in catalysis and materials science.
• Advanced Material Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and organic electronic materials due to its ability to influence solubility and electronic characteristics.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	1-(2,5-Difluorophenyl)-4,4,4-Trifluorobutane-1,3-Dione
CAS No.	35999-56-5
Molecular Formula	C10H5F5O2
Molecular Weight	252.14 g/mol
Synonyms	2,5-Difluorobenzoyltrifluoroacetone; 1-(2,5-Difluorophenyl)-1,3-butanedione, 4,4,4-trifluoro-; 4,4,4-Trifluoro-1-(2,5-difluorophenyl)butane-1,3-dione; 2',5'-Difluoro-4,4,4-trifluoroacetylacetophenone; DTFB; 1,3-Butanedione, 1-(2,5-difluorophenyl)-4,4,4-trifluoro-; 2,5-Difluorophenyl trifluoroacetyl ketone
EINECS	Contact for details

Quality Control

Our 1-(2,5-Difluorophenyl)-4,4,4-Trifluorobutane-1,3-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.