Description

3',4',5'-Trichloroacetophenone is a specialized halogenated aromatic ketone of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Its unique substitution pattern makes it an essential intermediate for researchers and manufacturers requiring high-purity, functionalized acetophenone derivatives.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those with halogenated aromatic cores.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides where the trichloro-substituted phenyl group imparts specific biological activity.
• Organic Synthesis Building Block: Employed in Friedel-Crafts acylation, nucleophilic substitution, and reduction reactions to create more complex chemical architectures.
• Material Science Research: Serves as a monomer or modifying agent in the development of specialty polymers and advanced organic materials.
• Chemical Reference Standard: Utilized in analytical laboratories for method development, calibration, and quality control testing.

Basic Information

Product Name	3',4',5'-Trichloroacetophenone
CAS No.	35981-65-8
Molecular Formula	C8H5Cl3O
Molecular Weight	229.48 g/mol
Synonyms	1-(3,4,5-Trichlorophenyl)ethanone; 3,4,5-Trichloroacetophenone; 3,4,5-Trichlorophenylethanone; Ethanone, 1-(3,4,5-trichlorophenyl)-; Acetophenone, 3',4',5'-trichloro-
EINECS	Contact for details

Quality Control

Our 3',4',5'-Trichloroacetophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.