Description

(1R)-(-)-10-Camphorsulfonic Acid is a high-purity, chiral organic acid derived from camphor. This compound serves as a versatile and highly effective chiral resolving agent and catalyst in asymmetric synthesis, prized for its ability to induce optical purity in target molecules. It is an essential material for pharmaceutical R&D, fine chemical synthesis, and academic research where precise stereochemical control is paramount.

Application

• Chiral Resolution Agent: Widely used for the optical resolution of racemic mixtures of amines, amino acids, and other basic compounds.
• Asymmetric Catalysis: Employed as a chiral Brønsted acid catalyst in a variety of enantioselective reactions, including Diels-Alder, Friedel-Crafts, and Mannich reactions.
• Pharmaceutical Intermediate: A key building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Analytical Chemistry: Used as a chiral selector or mobile phase additive in High-Performance Liquid Chromatography (HPLC) for enantiomer separation.
• Organic Synthesis: Functions as a mild and recyclable acid catalyst in protecting group chemistry and other synthetic transformations.
• Academic & Industrial Research: A standard reagent for method development in stereochemistry and catalysis studies.

Basic Information

Product Name	(1R)-(-)-10-Camphorsulfonic Acid
CAS No.	35963-20-3
Molecular Formula	C10H16O4S
Molecular Weight	232.30 g/mol
Synonyms	(-)-Camphor-10-sulfonic Acid; (1R)-(-)-Camphorsulfonic Acid; L-(-)-Camphorsulfonic Acid; (1R,4S)-(-)-Camphor-10-sulfonic Acid; (1R)-10-Camphorsulfonic Acid; (-)-CSA; D-Camphorsulfonic Acid (obsolete); (1R,4S)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic Acid
EINECS	252-783-8

Quality Control

Our (1R)-(-)-10-Camphorsulfonic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess), chemical assay, and impurity profiling to ensure it meets the stringent requirements for research and production. Certificates of Analysis (COA) with detailed HPLC, NMR, and optical rotation data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Enantiomeric Excess (ee)	≥ 99.0%
Optical Rotation [α]20/D	-20.0° to -22.0° (c=1 in H2O)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.