Description

(+)-3,4,6,9-Tetrahydro-5,10-Dihydroxy-8-Methoxy-2-(2-Oxopropyl)-2H-Naphtho[2,3-B]Pyran-6,9-Dione is a high-purity, complex organic compound belonging to the naphthopyranone class, valued for its specific stereochemistry and functional groups. This compound is a critical advanced pharmaceutical intermediate and a versatile building block in synthetic organic chemistry, enabling the development of novel active molecules. It is primarily sought by pharmaceutical R&D teams, contract research organizations (CROs), and manufacturers of fine chemicals for use in targeted synthesis programs.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug candidates, particularly in oncology and anti-infective research.
• Chemical Synthesis Building Block: Utilized in organic synthesis for constructing complex polycyclic frameworks due to its reactive ketone and hydroxyl functionalities.
• Academic & Industrial Research: Serves as a standard or starting material for methodological studies in catalysis, total synthesis, and medicinal chemistry.
• Biochemical Research: Potential use as a probe or inhibitor in enzymatic studies, leveraging its specific molecular structure.
• Material Science Precursor: Exploration into novel organic electronic materials or dyes derived from its conjugated naphthoquinone core.

Basic Information

Product Name	(+)-3,4,6,9-Tetrahydro-5,10-Dihydroxy-8-Methoxy-2-(2-Oxopropyl)-2H-Naphtho[2,3-B]Pyran-6,9-Dione
CAS No.	35887-77-5
Molecular Formula	C₁₇H₁₆O₇
Molecular Weight	332.31 g/mol
Synonyms	(+)-5,10-Dihydroxy-8-methoxy-2-(2-oxopropyl)-2,3,4,6,9,10-hexahydro-2H-naphtho[2,3-b]pyran-6,9-dione; (+)-LL-D49194 alpha 1; Antibiotic LL-D49194 alpha 1; (2R)-2-(2-Oxopropyl)-5,10-dihydroxy-8-methoxy-2,3,4,6,9,10-hexahydro-2H-naphtho[2,3-b]pyran-6,9-dione; (R)-2-(2-Oxopropyl)-5,10-dihydroxy-8-methoxy-2,3,4,6,9,10-hexahydro-2H-naphtho[2,3-b]pyran-6,9-dione
EINECS	Contact for details

Quality Control

Our production of (+)-3,4,6,9-Tetrahydro-5,10-Dihydroxy-8-Methoxy-2-(2-Oxopropyl)-2H-Naphtho[2,3-B]Pyran-6,9-Dione adheres to stringent quality protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral assay, to ensure it meets exacting research and pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.