Description

p-Diazonium Phenylphosphorylcholine is a specialized organophosphorus compound featuring a reactive diazonium group. This unique bifunctional structure makes it a valuable intermediate for the synthesis of advanced materials and bioactive molecules, particularly in surface modification and biomimetic chemistry. It is primarily sought by researchers and manufacturers in the pharmaceutical, biomedical device, and advanced polymer sectors for creating phospholipid-like surfaces and targeted conjugates.

Application

• Surface Functionalization Agent: For modifying materials (e.g., polymers, metals, silica) to create biomimetic, phosphorylcholine-based surfaces that resist protein adsorption and cell adhesion.
• Pharmaceutical Intermediate: In the research and development of novel drug delivery systems and targeted therapeutics that utilize phospholipid conjugates.
• Bioconjugation Reagent: For coupling phospholipid moieties to proteins, peptides, or other biomolecules via the reactive diazonium group for diagnostic or therapeutic applications.
• Polymer Synthesis: As a monomer or cross-linking agent in the production of specialty polymers with tailored interfacial properties for medical devices.
• Research Chemical: Used in academic and industrial R&D for studying cell-membrane interactions, hemocompatibility, and the development of anti-fouling coatings.
• Diagnostic Assay Development: For constructing biosensor surfaces or assay components that require specific, non-fouling interfacial chemistry.

Basic Information

Product Name	p-Diazonium Phenylphosphorylcholine
CAS No.	35697-91-7
Molecular Formula	C13H21N3O4P+ X- (where X- is typically a counterion like tetrafluoroborate)
Molecular Weight	Contact for details
Synonyms	4-Diazoniophenylphosphorylcholine; p-Diazoniumphenylphosphorylcholine; Phosphorylcholine p-diazonium salt; 2-[[(4-Diazoniophenyl)phosphono]oxy]-N,N,N-trimethylethanaminium; Diazonium phenylphosphorylcholine salt; 4-Diazophenylphosphorylcholine; MPC-diazonium salt analog; Biomimetic diazonium reagent
EINECS	Contact for details

Quality Control

Our p-Diazonium Phenylphosphorylcholine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing specifications such as assay (by NMR or HPLC), counterion content, and moisture levels is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place (recommended 2-8°C or as specified on the label) under an inert atmosphere if necessary. Due to its hygroscopic and light-sensitive nature, the material should be handled in a controlled environment to maintain stability. Keep container tightly sealed when not in use to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (by HPLC or NMR)	≥ 95%
Water Content (KF)	≤ 2.0%
Counterion Content	As specified (e.g., BF4-)
Solubility	Soluble in polar organic solvents (e.g., DMF, DMSO, methanol)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.