Description

3-Furancarboxylic Acid [(3As,6R)-3,3Aα,4,5,6Aα,7,9Aα,9Bβ-Octahydro-9-Methyl-3-Methylene-2-Oxospiro[Azuleno[4,5-B]Furan-6(2H),2'-Oxiran]-4β-Yl] Ester is a complex, high-purity organic ester with a unique spirocyclic and azulene-fused molecular architecture. This compound is of significant interest for advanced research and development, particularly in the synthesis of novel bioactive molecules and complex natural product analogs. It serves as a critical chiral building block and intermediate for pharmaceutical chemists and R&D laboratories focused on medicinal chemistry and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially those with complex polycyclic frameworks.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the synthesis of novel compound libraries for biological screening.
• Natural Product Synthesis: Serves as a sophisticated intermediate in the total or semi-synthesis of complex natural products containing furan and azulene motifs.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Industrial R&D: A valuable reagent for investigating new organic reactions and catalytic methodologies involving sterically hindered esters.

Basic Information

Item	Details
Product Name	3-Furancarboxylic Acid [(3As,6R)-3,3Aα,4,5,6Aα,7,9Aα,9Bβ-Octahydro-9-Methyl-3-Methylene-2-Oxospiro[Azuleno[4,5-B]Furan-6(2H),2'-Oxiran]-4β-Yl] Ester
CAS No.	35682-60-1
Molecular Formula	C22H26O5
Molecular Weight	370.44 g/mol
Synonyms	(3R,3aS,4R,6aR,7R,9aS,9bR)-9-Methyl-3-methylene-2-oxospiro[azuleno[4,5-b]furan-6(2H),2'-oxirane]-4-yl 3-furoate; 3-Furancarboxylic acid, (3R,3aS,4R,6aR,7R,9aS,9bR)-3,3a,4,5,6,6a,7,9a,9b-octahydro-9-methyl-3-methylene-2-oxospiro[azuleno[4,5-b]furan-6(2H),2'-oxiran]-4-yl ester; Spiro[azuleno[4,5-b]furan-6(2H),2'-oxiran] ester derivative; 3-Furoyl ester of a decahydroazulenofuranone epoxide.
EINECS	Contact for details

Quality Control

Our 3-Furancarboxylic Acid Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity, suitable for demanding research applications. All materials are characterized by modern analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be sensitive to prolonged exposure to moisture and elevated temperatures.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.