Description

2-Acetylamino-4-Trifluoromethyloxazole is a specialized heterocyclic building block featuring a trifluoromethylated oxazole core. This compound is valued for its unique molecular architecture, which combines the electron-withdrawing properties of the trifluoromethyl group with the versatile reactivity of the oxazole and acetamide functionalities. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition or receptor modulation.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, or insecticides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Material Science Precursor: Serves as a building block for advanced organic materials, such as liquid crystals or organic semiconductors, due to its rigid, fluorinated structure.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	2-Acetylamino-4-Trifluoromethyloxazole
CAS No.	35629-41-5
Molecular Formula	C6H5F3N2O2
Molecular Weight	194.11 g/mol
Synonyms	N-(4-(Trifluoromethyl)-1,3-oxazol-2-yl)acetamide; 2-Acetamido-4-(trifluoromethyl)oxazole; 2-Acetylamino-4-trifluoromethyloxazole; Acetamide, N-[4-(trifluoromethyl)-2-oxazolyl]-; 4-Trifluoromethyl-2-acetylaminooxazole
EINECS	Contact for details

Quality Control

Every batch of 2-Acetylamino-4-Trifluoromethyloxazole is manufactured under a strict quality management system. We employ advanced analytical techniques, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.