Description

cis-4-Methyl-Oxetane-2-Carboxylic Acid Methyl Ester is a high-value, chiral oxetane building block essential for advanced organic synthesis. This compound is prized for its rigid, strained oxetane ring system, which is used to modulate the physicochemical properties of target molecules, improving metabolic stability and bioavailability. It serves as a critical intermediate for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, kinase inhibitors, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science: Serves as a monomer or cross-linking agent for producing specialty polymers with unique thermal and mechanical properties.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis and organocatalysts.
• Chemical Biology Probes: Useful for incorporating the oxetane motif into probes for studying enzyme function and protein-ligand interactions.
• Flavor and Fragrance Industry: Potential intermediate for synthesizing complex odorants and flavor compounds.

Basic Information

Product Name	cis-4-Methyl-Oxetane-2-Carboxylic Acid Methyl Ester
CAS No.	35573-57-0
Molecular Formula	C6H10O3
Molecular Weight	130.14 g/mol
Synonyms	Methyl (3S,4R)-4-Methyloxetane-2-carboxylate; Methyl cis-4-Methyloxetane-2-carboxylate; (3S,4R)-4-Methyloxetane-2-carboxylic acid methyl ester; 4-Methyl-oxetane-2-carboxylic acid methyl ester, cis-; Oxetane-2-carboxylic acid, 4-methyl-, methyl ester, cis-; (cis)-Methyl 4-methyloxetane-2-carboxylate
EINECS	Contact for details

Quality Control

Every batch of cis-4-Methyl-Oxetane-2-Carboxylic Acid Methyl Ester is produced and tested under a strict quality management system. We ensure high chemical and isomeric purity through advanced analytical techniques, including chiral HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee consistency and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under an inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (cis-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.