Description

2-Butenoic Acid, 4-(4-Fluorophenyl)-4-Oxo-, (2Z)- is a specialized fluorinated organic compound belonging to the class of α,β-unsaturated ketocarboxylic acids. This high-purity intermediate is valued for its unique molecular scaffold, which combines a reactive butenoic acid moiety with a fluorinated aromatic ketone, making it a critical building block in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom and ketone group contribute to biological activity and environmental stability.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocycles and fluorinated compounds via reactions like Michael additions, cyclizations, and cross-couplings.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials with specific optical or electronic properties.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2-Butenoic Acid, 4-(4-Fluorophenyl)-4-Oxo-, (2Z)-
CAS No.	35513-38-3
Molecular Formula	C11H9FO3
Molecular Weight	208.19 g/mol
Synonyms	(2Z)-4-(4-Fluorophenyl)-4-oxo-2-butenoic acid; (Z)-4-(4-Fluorobenzoyl)but-2-enoic acid; 4-(4-Fluorobenzoyl)-2-butenoic acid (Z)-isomer; 4-(4-Fluorophenyl)-4-oxo-(2Z)-2-butenoic acid; 4-Oxo-4-(4-fluorophenyl)-(2Z)-2-butenoic acid; Fluorophenyl Oxobut-2-enoic Acid; 35513-38-3
EINECS	Contact for details

Quality Control

Our 2-Butenoic Acid, 4-(4-Fluorophenyl)-4-Oxo-, (2Z)- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (Isomeric, HPLC)	≥ 99.0% (Z-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.