Description

2-(o-Chlorophenyl)Oxetane is a specialized heterocyclic building block featuring an oxetane ring fused to an ortho-chlorinated benzene moiety. This unique structure makes it a valuable intermediate in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the oxetane ring can modulate bioavailability and environmental persistence.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, resins, and liquid crystals with tailored thermal and optical properties.
• Ligand and Catalyst Development: Employed in the synthesis of chiral ligands and organocatalysts for asymmetric synthesis, leveraging the stereogenic center of the oxetane ring.
• Chemical Biology Probes: Utilized as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Academic & Industrial R&D: A fundamental reagent for methodological studies in organic chemistry, including ring-opening and annulation reactions.

Basic Information

Item	Detail
Product Name	2-(o-Chlorophenyl)Oxetane
CAS No.	35509-71-8
Molecular Formula	C9H9ClO
Molecular Weight	168.62 g/mol
Synonyms	2-(2-Chlorophenyl)oxetane; o-Chlorophenyloxetane; 2-(2-Chlorophenyl)oxacyclobutane; 2-Chlorophenyloxetane; Oxetane, 2-(2-chlorophenyl)-; 35509-71-8; 2-(2-Chlorophenyl)-1-oxacyclobutane
EINECS	Contact for details

Quality Control

Every batch of 2-(o-Chlorophenyl)Oxetane is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.