Description

12β-Acetoxy-5α-Androstane is a high-purity steroidal intermediate of significant importance in advanced pharmaceutical synthesis. This compound serves as a critical building block for the development of specialized steroid-based active pharmaceutical ingredients (APIs) and research compounds. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in steroid chemistry and hormone-related therapeutic development.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex steroid-based drugs and APIs.
• Research & Development: Used in academic and industrial laboratories for exploring new synthetic pathways and novel steroid derivatives.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in steroid analysis.
• Fine Chemical Synthesis: Employed in the production of other high-value, specialized androstane derivatives for various applications.

Basic Information

Product Name	12β-Acetoxy-5α-Androstane
CAS No.	35487-70-8
Molecular Formula	C21H32O3
Molecular Weight	332.48 g/mol
Synonyms	12β-Acetoxy-5α-androstane; 5α-Androstan-12β-ol, acetate; 12β-Acetoxyandrostane; Androstane-12β-ol acetate; 12β-Acetoxy-5α-androstan-3-one (related ketone); 12-Acetoxy-5α-androstane; (5α,12β)-Androstan-12-yl acetate
EINECS	Contact for details

Quality Control

Our 12β-Acetoxy-5α-Androstane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a detailed Certificate of Analysis (COA). We adhere to cGMP guidelines where applicable to support its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.