Description

2-Spirohydantoin-6,7-Dimethoxytetrahydronaphthalene is a specialized heterocyclic organic compound featuring a spiro-hydantoin moiety fused to a dimethoxytetralin scaffold. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, particularly those targeting neurological and cardiovascular pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a core scaffold for designing and synthesizing new chemical entities for biological screening and structure-activity relationship (SAR) studies.
• Neurological Drug Development: Used in research programs focused on central nervous system (CNS) disorders due to its structural similarity to bioactive tetralin derivatives.
• Chemical Synthesis Building Block: Employed in multi-step organic syntheses to introduce the spirohydantoin pharmacophore into target molecules.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	2-Spirohydantoin-6,7-Dimethoxytetrahydronaphthalene
CAS No.	35485-64-4
Molecular Formula	C₁₄H₁₆N₂O₄
Molecular Weight	276.29 g/mol
Synonyms	6,7-Dimethoxy-1,2,3,4-tetrahydro-2-spiro-4'-imidazolidine-2',5'-dionenaphthalene; 2-Spiro-5-hydantoin-6,7-dimethoxy-1,2,3,4-tetrahydronaphthalene; 6,7-Dimethoxy-2-(2,5-dioxoimidazolidin-4-yl)-1,2,3,4-tetrahydronaphthalene; 2-(6,7-Dimethoxy-1,2,3,4-tetrahydro-2-naphthyl)hydantoin; 2-(6,7-Dimethoxy-1,2,3,4-tetrahydronaphthalen-2-yl)imidazolidine-2,4-dione
EINECS	Contact for details

Quality Control

Our 2-Spirohydantoin-6,7-Dimethoxytetrahydronaphthalene is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.