Description

Leucomycin V 4''-Butanoate 3-Propanoate is a semi-synthetic derivative of the leucomycin (kitasamycin) macrolide antibiotic, specifically engineered for enhanced stability and bioavailability. This chemical modification is crucial for developing advanced pharmaceutical intermediates with improved pharmacokinetic profiles. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel antibacterial agents and veterinary medicines.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of next-generation macrolide antibiotics for human and veterinary use.
• Antibacterial Research: Used in microbiological and pharmacological studies to investigate structure-activity relationships (SAR) against resistant bacterial strains.
• Veterinary Medicine Development: A critical precursor in formulating advanced treatments for bacterial infections in livestock and companion animals.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial production of specialized antibiotic compounds.

Basic Information

Product Name	Leucomycin V 4''-Butanoate 3-Propanoate
CAS No.	35457-81-9
Molecular Formula	C48H81NO17
Molecular Weight	944.16 g/mol
Synonyms	Kitasamycin V 4''-Butyrate 3-Propionate; Leucomycin V 3,4''-Diesters; 9,3''-Di-O-acetyl-4''-O-butyryl leucomycin V; 4''-O-Butanoyl-3-O-propanoyl leucomycin V; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione 3-propanoate 4''-butanoate
EINECS	Contact for details

Quality Control

Our Leucomycin V 4''-Butanoate 3-Propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Long-term storage under inert atmosphere is recommended.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.