Description

2-Iodo-1-Methoxy-3-Methylbenzene is a versatile iodoanisole derivative, a key halogenated aromatic building block in advanced organic synthesis. Its primary commercial value lies in its role as a crucial intermediate for constructing complex molecules in pharmaceutical and agrochemical research and development. This compound is essential for chemists and manufacturers in the fine chemical, life science, and material science industries who require high-purity, reliable intermediates for coupling reactions and functional group transformations.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic motifs for biological activity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the iodine atom can be further functionalized or act as a directing group.
• Material Science Research: Acts as a monomer or building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions such as Suzuki, Stille, and Sonogashira couplings to form biaryl and other complex structures.
• Organic Synthesis & Process Chemistry: Employed in academic and industrial R&D labs for method development and the scalable synthesis of complex organic molecules.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands for metal complexes used in catalysis.

Basic Information

Product Name	2-Iodo-1-Methoxy-3-Methylbenzene
CAS No.	35387-94-1
Molecular Formula	C8H9IO
Molecular Weight	248.06 g/mol
Synonyms	2-Iodo-3-methylanisole; 1-Iodo-2-methoxy-6-methylbenzene; 3-Methyl-2-iodoanisole; 2-Iodo-m-cresol methyl ether; 6-Methyl-2-iodoanisole; o-Iodo-m-cresol methyl ether; 2-Iodo-3-methyl-1-methoxybenzene
EINECS	Contact for details

Quality Control

Our 2-Iodo-1-Methoxy-3-Methylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ISO standards for reliable integration into regulated synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.