Description

N,o-Bis(Trimethylsilyl)Carbamate is a versatile organosilicon reagent primarily used as a silylating agent and protecting group in complex organic synthesis. Its value lies in its ability to efficiently introduce trimethylsilyl groups, facilitating reactions and purifications in the production of high-value intermediates. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable and high-purity building blocks for their synthetic processes.

Application

• Pharmaceutical Intermediate Synthesis: Acts as a key protecting group for carbamates and amines in the multi-step synthesis of active pharmaceutical ingredients (APIs).
• Agrochemical Production: Used in the manufacture of advanced pesticides and herbicides where selective silylation is required.
• Peptide Chemistry: Employed for the temporary protection of amino groups during solid-phase and solution-phase peptide synthesis.
• Derivatization Agent for Analysis: Utilized in gas chromatography (GC) and mass spectrometry (MS) to enhance the volatility and detectability of polar compounds.
• Organometallic & Catalyst Research: Serves as a precursor or modifying agent in the development of novel catalysts and organometallic complexes.
• Specialty Polymer Modification: Used to introduce silyl functionalities into polymer backbones, altering material properties like solubility and thermal stability.

Basic Information

Product Name	N,o-Bis(Trimethylsilyl)Carbamate
CAS No.	35342-88-2
Molecular Formula	C7H19NO2Si2
Molecular Weight	205.40 g/mol
Synonyms	Carbamic Acid, N,O-Bis(trimethylsilyl)-; BTS; O,N-Bis(trimethylsilyl)carbamate; Bis(trimethylsilyl) Carbamate; Trimethylsilyl Carbamate; N,O-Bis(trimethylsilyl)carbamic Acid; TMS-Carbamate; (Trimethylsilyloxy)(trimethylsilylamino)methanone
EINECS	Contact for details

Quality Control

Our N,o-Bis(Trimethylsilyl)Carbamate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including GC, HPLC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific impurity limits is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.