Description

11α,13-Dihydroxy-2,12β-Dimethoxypicrasa-2,14-Diene-1,16-Dione is a specialized, high-purity chemical compound belonging to the quassinoid class of natural products. This compound matters for its role as a key intermediate and reference standard in advanced pharmaceutical research and development, particularly in the study of bioactive natural products. It is primarily needed by R&D laboratories, academic institutions, and pharmaceutical companies focused on oncology, parasitology, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate or reference standard in the synthesis and study of novel bioactive compounds, particularly those with anti-cancer or anti-parasitic potential.
• Natural Product Chemistry: Used as a purified standard for the identification, quantification, and isolation of related quassinoids from complex plant extracts.
• Academic & Institutional Research: Employed in biochemical and pharmacological studies to investigate structure-activity relationships (SAR) and mechanisms of action.
• Analytical Reference Material: Provides a high-purity benchmark for analytical methods development, including HPLC, LC-MS, and NMR, ensuring accurate compound identification and purity assessment.
• Pre-clinical Studies: Utilized in in-vitro and in-vivo testing to evaluate the efficacy and toxicity profiles of new drug candidates derived from the quassinoid scaffold.

Basic Information

Product Name	11α,13-Dihydroxy-2,12β-Dimethoxypicrasa-2,14-Diene-1,16-Dione
CAS No.	35334-39-5
Molecular Formula	C22H28O7
Molecular Weight	404.45 g/mol
Synonyms	11α,13-Dihydroxy-2β,12-dimethoxypicrasa-2,14-diene-1,16-dione; 2,12-Dimethoxy-11α,13-dihydroxypicrasa-2,14-diene-1,16-dione; Ailanthone derivative; Quassinoid derivative; Bruceine D analogue; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 11α,13-Dihydroxy-2,12β-Dimethoxypicrasa-2,14-Diene-1,16-Dione is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.