Description

(2R)-2-[2-[(2S)-5-Hydroxy-2,7-Dimethyl-2H-1-Benzopyran-2-Yl]Ethyl]-3,3-Dimethylcyclohexanecarboxylic Acid CAS NO 35316-35-9 is a high-purity, optically active benzopyran derivative with a complex stereochemistry that is critical for its biological activity. This compound serves as a key chiral intermediate in the synthesis of advanced pharmaceutical agents, where its specific stereoconfiguration is essential for efficacy and safety. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic compounds, particularly in areas requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially those targeting specific biological pathways.
• Chiral Synthesis: Utilized in asymmetric synthesis to construct complex molecules with defined stereocenters for medicinal chemistry applications.
• Biochemical Research: Serves as a reference standard or probe in studying enzyme interactions and receptor binding mechanisms.
• Fine Chemical Production: Used in the manufacture of high-value specialty chemicals where optical purity is a paramount requirement.
• API Development: Employed in the research and development stages of Active Pharmaceutical Ingredient (API) process chemistry.

Basic Information

Product Name	(2R)-2-[2-[(2S)-5-Hydroxy-2,7-Dimethyl-2H-1-Benzopyran-2-Yl]Ethyl]-3,3-Dimethylcyclohexanecarboxylic Acid
CAS No.	35316-35-9
Molecular Formula	C22H30O4
Molecular Weight	358.47 g/mol
Synonyms	5-Hydroxy-2,7-dimethyl-2-[(1R)-2-[(1S)-3,3-dimethyl-1-(carboxy)cyclohexyl]ethyl]-2H-1-benzopyran; (2R,2'S)-5-Hydroxy-2,7-dimethyl-2-[2'-(3,3-dimethyl-1-cyclohexylcarboxylic acid)ethyl]chromane; Chromane-2-carboxylic acid derivative; Optically active benzopyran carboxylic acid; Chiral chromanecarboxylic acid intermediate; (2R,2'S)-Chromane derivative; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our production of (2R)-2-[2-[(2S)-5-Hydroxy-2,7-Dimethyl-2H-1-Benzopyran-2-Yl]Ethyl]-3,3-Dimethylcyclohexanecarboxylic Acid adheres to stringent quality protocols suitable for pharmaceutical-grade intermediates. All batches undergo rigorous analytical testing including chiral purity verification by HPLC to ensure stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.