Description

4-Hydroxyochratoxin A is a significant hydroxylated derivative of the mycotoxin ochratoxin A, representing a key metabolite and analytical reference standard. This compound is essential for researchers and quality control laboratories focused on mycotoxin analysis and toxicological studies. It is primarily used in the food safety, agricultural, and pharmaceutical industries for method development, calibration, and investigating the metabolic pathways and toxicity profiles of ochratoxins.

Application

• Analytical Reference Standard: Primary use as a high-purity certified standard for the quantitative and qualitative analysis of ochratoxin A and its metabolites via HPLC, LC-MS/MS, and ELISA techniques.
• Food & Feed Safety Testing: Critical for developing and validating testing protocols to monitor and control mycotoxin contamination in grains, coffee, wine, and animal feed.
• Metabolic Pathway Research: Used in biochemical and pharmacological studies to elucidate the detoxification, bioactivation, and excretion pathways of ochratoxin A in humans and animals.
• Toxicological Studies: Serves as a reagent in in vitro and in vivo research to assess the comparative toxicity, carcinogenicity, and nephrotoxic effects of ochratoxin derivatives.
• Quality Control & Method Development: Employed by testing laboratories and manufacturers of diagnostic kits to ensure accuracy, precision, and compliance with regulatory methods (e.g., AOAC, ISO, EN).
• Pharmaceutical Impurity Profiling: Potential use in stability studies and impurity identification for pharmaceuticals derived from fungal fermentation or natural sources.

Basic Information

Item	Detail
Product Name	4-Hydroxyochratoxin A
CAS No.	35299-87-7
Molecular Formula	C20H18ClNO6
Molecular Weight	403.81 g/mol
Synonyms	4'-Hydroxyochratoxin A; (R)-4'-Hydroxyochratoxin A; 7-Hydroxyochratoxin A; 4-OH-OTA; Ochratoxin A 4'-hydroxy derivative; 2-[(3R)-8-Chloro-3,4-dihydro-3-hydroxy-1-methyl-6-oxo-7-isochromanyl]carbonyl]-4-hydroxy-D-phenylalanine; 4'-Hydroxy-OTA
EINECS	Contact for details

Quality Control

Our 4-Hydroxyochratoxin A is manufactured and handled under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for analytical applications. Each lot is characterized using advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation. The material should be stored in a cool, dry, and well-ventilated area dedicated for research chemicals.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.