Description

2-Bromo-3,4,5-Trimethoxy-Benzaldehyde is a versatile aromatic aldehyde derivative, serving as a crucial advanced intermediate in organic synthesis. Its value lies in the strategic placement of bromine and methoxy groups, which enable selective functionalization for constructing complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry research for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging its reactive aldehyde and halogen sites.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Intermediate in the manufacture of dyes, pigments, and specialty polymers where its substituted benzaldehyde core is incorporated.
• Academic and R&D: Employed in university and institutional laboratories for methodological studies in cross-coupling reactions and heterocycle formation.
• Material Science Research: Precursor for organic electronic materials and liquid crystals due to its electron-donating methoxy groups and planar structure.

Basic Information

Product Name	2-Bromo-3,4,5-Trimethoxy-Benzaldehyde
CAS No.	35274-53-4
Molecular Formula	C10H11BrO4
Molecular Weight	275.10 g/mol
Synonyms	3,4,5-Trimethoxy-2-bromobenzaldehyde; Benzaldehyde, 2-bromo-3,4,5-trimethoxy-; 2-Bromo-3,4,5-trimoxybenzaldehyde; 2-Bromogallic aldehyde trimethyl ether; 3,4,5-Trimethoxy-2-bromobenzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-Bromo-3,4,5-Trimethoxy-Benzaldehyde is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	98 - 102 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.