Description

9-Methoxy-α-Lapachone is a synthetic derivative of the naturally occurring quinone, lapachone, characterized by a methoxy substitution at the 9-position. This structural modification enhances its stability and can fine-tune its biological activity, making it a valuable intermediate and research chemical for pharmaceutical and biochemical applications. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing novel therapeutic agents and studying enzyme inhibition.

Application

• Pharmaceutical Research & Development: Serves as a key synthetic intermediate or a lead compound in the discovery of new anticancer, antimicrobial, and anti-inflammatory agents.
• Biochemical Studies: Used as a tool compound to investigate the mechanisms of quinone-based compounds, particularly their role in inducing apoptosis and modulating cellular redox states.
• Enzyme Inhibition Studies: Acts as a potential inhibitor for specific enzymes like topoisomerases, making it relevant for targeted cancer therapy research.
• Fine Chemical Synthesis: Employed as a specialized building block for the synthesis of more complex quinone derivatives with tailored biological properties.
• Academic Research: Utilized in universities and laboratories for fundamental studies in organic chemistry, medicinal chemistry, and chemical biology.

Basic Information

Product Name	9-Methoxy-α-Lapachone
CAS No.	35241-80-6
Molecular Formula	C16H14O4
Molecular Weight	270.28 g/mol
Synonyms	9-Methoxy-α-lapachone; 9-Methoxylapachone; 2,2-Dimethyl-9-methoxy-2H-naphtho[1,2-b]pyran-5,6-dione; 9-Methoxy-3,4-dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione; 9-Methoxy-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione
EINECS	Contact for details

Quality Control

Our 9-Methoxy-α-Lapachone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to light and oxidation, prolonged exposure to air and light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.