Description

2-Diazomalonic Acid Ditert-Butyl Ester is a versatile diazo compound and a key reagent in organic synthesis. This compound is valued for its role as a carbene precursor, enabling efficient carbon-carbon and carbon-heteroatom bond formation under mild conditions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Carbene Generation: Serves as a stable and convenient source of carbenes for cyclopropanation, C-H insertion, and X-H insertion reactions.
• Pharmaceutical Intermediates: Used in the synthesis of complex, biologically active molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Employed in the development of novel pesticides and herbicides through efficient ring-forming and functionalization steps.
• Polymer & Material Science: Acts as a cross-linking agent or monomer precursor for specialty polymers and functional materials.
• Academic & Industrial R&D: A fundamental tool in methodology development and exploratory synthesis within organic chemistry laboratories.
• Peptide Modification: Can be used for selective labeling or modification of amino acid side chains via carbene chemistry.

Basic Information

Product Name	2-Diazomalonic Acid Ditert-Butyl Ester
CAS No.	35207-75-1
Molecular Formula	C11H18N2O4
Molecular Weight	242.27 g/mol
Synonyms	Di-tert-butyl diazomalonate; Ditert-butyl diazomalonate; Diazomalonic acid di-tert-butyl ester; 2-Diazo-1,3-di-tert-butyl malonate; tert-Butyl diazomalonate; Diazomalonic Acid Bis(1,1-dimethylethyl) Ester; Malonic acid, 2-diazo-, 1,3-bis(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our 2-Diazomalonic Acid Ditert-Butyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, minimize exposure during handling.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.