Description

Ethyl 3-Hydroxy-2,2-Dimethyl-3-Phenylpropanoate is a high-purity organic ester compound valued for its role as a versatile chiral building block and intermediate in advanced chemical synthesis. Its molecular structure, featuring both hydroxyl and ester functional groups on a tertiary carbon center, makes it a critical precursor for producing complex molecules with high stereochemical control. This compound is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers engaged in creating active pharmaceutical ingredients (APIs), agrochemicals, and specialty fragrances.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced pesticides and herbicides, where its stereochemistry influences biological activity.
• Fine Chemical Production: Serves as a building block for specialty chemicals, including liquid crystals, advanced polymers, and performance materials.
• Flavor and Fragrance Industry: Employed in the synthesis of complex ester-based aroma compounds and odorants.
• Academic & R&D: A valuable reagent in organic chemistry research for methodology development and the study of stereoselective reactions.
• Catalyst and Ligand Preparation: Utilized in the synthesis of chiral ligands and organocatalysts for asymmetric catalysis.

Basic Information

Product Name	Ethyl 3-Hydroxy-2,2-Dimethyl-3-Phenylpropanoate
CAS No.	35022-34-5
Molecular Formula	C₁₃H₁₈O₃
Molecular Weight	222.28 g/mol
Synonyms	Ethyl 3-Hydroxy-2,2-Dimethyl-3-Phenylpropionate; 3-Hydroxy-2,2-dimethyl-3-phenylpropionic Acid Ethyl Ester; 2,2-Dimethyl-3-hydroxy-3-phenylpropionic Acid Ethyl Ester; Ethyl 3-Phenyl-3-hydroxy-2,2-dimethylpropanoate; β-Hydroxy-β-phenylisovaleric Acid Ethyl Ester; EHDMPP; NSC 163022
EINECS	Contact for details

Quality Control

Our Ethyl 3-Hydroxy-2,2-Dimethyl-3-Phenylpropanoate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) detailing identity, assay, impurity profile, and physical characteristics are provided and available upon request, supporting compliance in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product may be hygroscopic; ensure containers are sealed after use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (Typical)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.