Description

Azacyclotridecane-2-Thione, 1-Methyl- is a specialized heterocyclic organic compound featuring a 13-membered lactam (azacyclotridecanone) ring system with a thione (C=S) group at the 2-position and a methyl substituent on the nitrogen. This unique structure makes it a valuable chemical intermediate and building block for advanced synthesis in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, complex natural product analogs, and macrocyclic compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel macrocyclic drug candidates, particularly those targeting neurological or anti-infective pathways.
• Agrochemical Research: Used as a building block for developing new classes of herbicides, fungicides, or plant growth regulators with complex ring systems.
• Ligand Synthesis: Acts as a starting material for creating specialized chelating agents or catalysts used in asymmetric synthesis and metal complexation.
• Material Science: Potential monomer or modifier in the development of specialty polymers with unique thermal or mechanical properties.
• Academic & Industrial R&D: Employed in exploratory chemistry for constructing complex nitrogen- and sulfur-containing heterocycles of scientific interest.

Basic Information

Product Name	Azacyclotridecane-2-Thione, 1-Methyl-
CAS No.	34949-18-3
Molecular Formula	C₁₂H₂₃NS
Molecular Weight	213.38 g/mol
Synonyms	1-Methylazacyclotridecane-2-thione; 1-Methyl-2-thioxoazacyclotridecane; N-Methylazacyclotridecane-2-thione; 1-Methyl-2-thioxo-1-azacyclotridecane; 2-Thioxo-1-methylazacyclotridecan; N-Methyl-2-thioxoazacyclotridecan; Lactam Thioamide Derivative; Macrocyclic Thiolactam
EINECS	Contact for details

Quality Control

Our Azacyclotridecane-2-Thione, 1-Methyl- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), related substances, and physical characteristics are provided and available upon request. We support cGMP compliance for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.