Description

2-Bromo-3'-Chloropropiophenone is a halogenated aromatic ketone that serves as a versatile and critical building block in advanced organic synthesis. Its molecular structure, featuring both bromine and chlorine substituents, makes it a valuable precursor for constructing complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. This intermediate is essential for chemists and process developers in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific halogenated motifs into target compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated phenylpropane structures.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where its halogen atoms contribute to biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing halogenated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) due to the reactive bromine moiety.
• Fine Chemical Manufacturing: Employed in custom synthesis and contract manufacturing for producing specialty chemicals and complex organic molecules.
• Academic & R&D Laboratories: Utilized in universities and research institutions for methodological studies and the discovery of new synthetic pathways.

Basic Information

Item	Details
Product Name	2-Bromo-3'-Chloropropiophenone
CAS No.	34911-51-8
Molecular Formula	C9H8BrClO
Molecular Weight	247.52 g/mol
Synonyms	1-(3-Chlorophenyl)-2-bromopropan-1-one; 3'-Chloro-2-bromopropiophenone; 2-Bromo-1-(3-chlorophenyl)propan-1-one; α-Bromo-3'-chloropropiophenone; Propiophenone, 2-bromo-3'-chloro-; 2-Bromopropiophenone, 3'-chloro derivative; 34911-51-8; NSC 403119
EINECS	Contact for details

Quality Control

Our 2-Bromo-3'-Chloropropiophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.