Description

2-(Dimethylamino)Ethyl 5-Oxo-L-Prolinate is a specialized amino acid derivative and a key intermediate in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of pharmaceuticals and bioactive compounds. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing novel active ingredients and chiral building blocks.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of proline-based drug candidates, including enzyme inhibitors and receptor modulators.
• Peptidomimetic Research: Used in the design and development of peptidomimetics and constrained peptides to improve metabolic stability and bioavailability.
• Chiral Synthesis: Serves as a chiral auxiliary or precursor in asymmetric synthesis for producing enantiomerically pure compounds.
• Agrochemical Development: Employed in the research and production of advanced, targeted agrochemicals and plant growth regulators.
• Bioconjugation Chemistry: Utilized in the modification of biomolecules for creating targeted drug delivery systems or diagnostic probes.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	2-(Dimethylamino)Ethyl 5-Oxo-L-Prolinate
CAS No.	34834-78-1
Molecular Formula	C9H16N2O3
Molecular Weight	200.24 g/mol
Synonyms	L-Pyroglutamic acid 2-(dimethylamino)ethyl ester; 5-Oxo-L-proline 2-(dimethylamino)ethyl ester; 2-(Dimethylamino)ethyl L-pyroglutamate; 2-(Dimethylamino)ethyl (S)-5-oxopyrrolidine-2-carboxylate; DMAP-Glu(OtBu)-OH derivative (contextual); Amino acid ester derivative; (S)-1-(2-(Dimethylamino)ethoxy)-5-oxopyrrolidine-2-carboxylic acid (tautomeric form)
EINECS	Contact for details

Quality Control

Our 2-(Dimethylamino)Ethyl 5-Oxo-L-Prolinate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure compliance with exacting standards for research and production use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.