Description

Mezerein CAS NO 34807-41-5 is a bioactive diterpene ester, a key phytochemical constituent derived from plants of the *Thymelaeaceae* family, notably *Daphne mezereum*. This compound is of significant interest for its potent biological activity, serving as a critical reference standard and a valuable tool compound in pharmacological and biochemical research. It is primarily sought after by research institutions, pharmaceutical R&D laboratories, and manufacturers of high-purity biochemical reagents.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies investigating protein kinase C (PKC) activation, tumor promotion, and cell signaling pathways.
• Biochemical Assay Development: Serves as a critical tool compound for calibrating assays and validating methods related to PKC activity and other enzymatic studies.
• Pharmaceutical R&D: Employed in early-stage drug discovery for screening and evaluating compounds that interact with PKC and related biological targets.
• Natural Product Analysis: Acts as a key marker compound for the quality control and standardization of botanical extracts from *Daphne* species and related medicinal plants.
• Academic Research: Utilized in university and institutional labs for fundamental research in toxicology, dermatology, and cancer biology.
• Reference Material Production: Supplied to certified reference material (CRM) producers for creating authenticated standards for analytical laboratories.

Basic Information

Product Name	Mezerein
CAS No.	34807-41-5
Molecular Formula	C38H38O10
Molecular Weight	654.70 g/mol
Synonyms	Mezerein; Daphnetoxin 12,13-diacetate 20-benzoate; NSC 380292; 5,12b-Diacetoxy-3-benzoyloxy-9,14-dihydroxy-6,7-epoxy-8,11,13-podocarpatrien-1-one; 12b-Acetoxy-3-benzoyloxy-9,14-dihydroxy-5-acetoxy-6,7-epoxy-8,11,13-podocarpatrien-1-one
EINECS	Contact for details

Quality Control

Our Mezerein is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods (NMR, MS) for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.