Description

3-Chloro-4-Hydroxy-1,4-Diphenyl-2-Butanone is a specialized organic intermediate featuring a chlorinated β-hydroxy ketone scaffold flanked by phenyl groups. This unique structure makes it a valuable synthon for constructing complex molecules in pharmaceutical and fine chemical research. It is primarily sought after by R&D chemists and process development scientists for applications in medicinal chemistry and advanced organic synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly those with chiral centers or complex carbon skeletons.
• Medicinal Chemistry Research: Used in the exploration of structure-activity relationships (SAR) for new therapeutic agents.
• Fine Chemical Synthesis: Serves as a precursor for the production of specialty chemicals, flavors, and fragrances.
• Academic & Industrial R&D: Employed in methodological studies and the development of novel synthetic pathways.
• Chiral Synthesis: The molecule's structure can be utilized in the preparation of enantiomerically pure compounds.
• Chemical Reference Standard: Used for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	3-Chloro-4-Hydroxy-1,4-Diphenyl-2-Butanone
CAS No.	34737-56-9
Molecular Formula	C₁₆H₁₅ClO₂
Molecular Weight	274.74 g/mol
Synonyms	3-Chloro-4-hydroxy-1,4-diphenylbutan-2-one; 1,4-Diphenyl-3-chloro-4-hydroxy-2-butanone; 3-Chloro-4-hydroxy-1,4-diphenylbutan-2-one; 2-Butanone, 3-chloro-4-hydroxy-1,4-diphenyl-; 3-Chloro-4-hydroxy-1,4-diphenyl-2-butanone; 4-Hydroxy-3-chloro-1,4-diphenyl-2-butanone
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Hydroxy-1,4-Diphenyl-2-Butanone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed specifications, including assay by HPLC and impurity profiles. Our quality systems are designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.