Description

2-Chloro-3-Nitrobenzonitrile is a versatile aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of its chloro and nitro substituents, which enable selective functionalization for constructing complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those with benzamide or heterocyclic backbones.
• Agrochemical Synthesis: Building block for developing herbicides, fungicides, and insecticides, leveraging its nitro and cyano groups for further chemical modification.
• Dye and Pigment Manufacturing: Intermediate in the production of specialized azo dyes and high-performance pigments.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and polymers with specific electronic properties.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions like Suzuki, Sonogashira, or Buchwald-Hartwig amination for C-C and C-N bond formation.
• Nucleophilic Aromatic Substitution: The activated nitro and chloro groups make it an excellent electrophile for displacement reactions with various nucleophiles.

Basic Information

Item	Details
Product Name	2-Chloro-3-Nitrobenzonitrile
CAS No.	34662-24-3
Molecular Formula	C7H3ClN2O2
Molecular Weight	182.56 g/mol
Synonyms	2-Chloro-3-nitrobenzonitrile; 3-Nitro-2-chlorobenzonitrile; Benzonitrile, 2-chloro-3-nitro-; 2-Chloro-3-nitrobenzenecarbonitrile; o-Chloro-m-nitrobenzonitrile; NSC 403119; 34662-24-3
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Nitrobenzonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request, providing full traceability and compliance assurance for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	108 - 112 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.