Description

2-Bromo-1-Cyclopropyl-2-Phenylethanone is a versatile and high-value brominated ketone building block in organic synthesis. This compound matters for its unique molecular architecture, combining a reactive α-bromo ketone moiety with a cyclopropyl group, which is prized for introducing ring strain and conformational rigidity into target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of advanced herbicides, fungicides, and insecticides, where the cyclopropyl group can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for specialty polymers and liquid crystals, leveraging its rigid structure to influence material properties.
• Organic Synthesis Reagent: Employed in various name reactions, such as Favorskii rearrangements and nucleophilic substitution reactions, to create complex, functionalized organic molecules.
• Chemical Biology Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme mechanisms and protein-ligand interactions.

Basic Information

Product Name	2-Bromo-1-Cyclopropyl-2-Phenylethanone
CAS No.	34650-68-5
Molecular Formula	C11H11BrO
Molecular Weight	239.11 g/mol
Synonyms	2-Bromo-1-cyclopropyl-2-phenylethan-1-one; α-Bromocyclopropyl phenyl ketone; Phenacylcyclopropyl bromide; 2-Bromo-2-phenyl-1-cyclopropylethanone; Cyclopropyl phenacyl bromide; (2-Bromo-2-phenylethylidene)cyclopropane; 34650-68-5; NSC 403058
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-Cyclopropyl-2-Phenylethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.