Description

Boromycin is a unique boron-containing macrolide antibiotic with a complex polyketide structure, identified by CAS NO 34524-20-4. This compound is valued for its potent biological activity, particularly as a selective ionophore for potassium ions, which underpins its significant research applications in biochemistry and microbiology. It is primarily sought by research institutions and pharmaceutical development laboratories for use in antimicrobial studies, ion transport mechanism research, and as a lead compound in drug discovery.

Application

• Antimicrobial Research: Investigation of its potent activity against Gram-positive bacteria, mycobacteria, and some fungi.
• Biochemical Probe: Used as a specific potassium ionophore to study ion transport across biological membranes and cellular physiology.
• Pharmaceutical Development: Serves as a lead compound for the design and synthesis of novel antibiotics and ion-channel modulators.
• Mechanistic Studies: Research into the mode of action of boron-containing natural products and polyketide antibiotics.
• Chemical Biology: Tool compound for exploring bacterial cell wall synthesis and membrane potential disruption.

Basic Information

Product Name	Boromycin
CAS No.	34524-20-4
Molecular Formula	C45H74BNO15
Molecular Weight	879.88 g/mol
Synonyms	Boromycin; Antibiotic X-5108; Antibiotic X 5108; Boromycin A; NSC 169467; 5-[(2R,3S,4R,5S,6R)-5-[(3S,5S,7S,9S,10R,12S,13R,14S,15R)-3-[(2R,4R,5S,6S)-4,5-Dihydroxy-4,6-dimethyloxan-2-yl]oxy-14-ethyl-7,12,15-trihydroxy-4,10-dimethyl-1-oxaspiro[4.4]nonadec-13-en-2-yl]-3,4-dihydroxy-6-methyloxan-2-yl]oxy-2-methyl-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our Boromycin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research purposes. Each lot undergoes comprehensive analytical testing, including HPLC for purity confirmation and spectroscopic methods for structural verification. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.