Description

2-Propanone, 1,1,1-Trifluoro-3-(Phenylthio)- is a specialized fluorinated ketone derivative that serves as a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring both a trifluoroacetone moiety and a phenylthio group, makes it a critical intermediate for introducing fluorinated motifs into target molecules, which can dramatically alter their physical, chemical, and biological properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atoms contribute to improved weather resistance and biological activity.
• Material Science Precursor: Serves as a monomer or modifier in the production of specialty polymers and coatings with unique surface properties and chemical resistance.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis, leveraging the sulfur and carbonyl functionalities.
• Fluorine Chemistry Research: A fundamental reagent in academic and industrial R&D for exploring new fluorination methodologies and reaction pathways.
• Liquid Crystal and Electronic Material Synthesis: Potential intermediate for creating fluorinated components used in display technologies and organic electronics.

Basic Information

Product Name	2-Propanone, 1,1,1-Trifluoro-3-(Phenylthio)-
CAS No.	34509-09-6
Molecular Formula	C9H7F3OS
Molecular Weight	220.21 g/mol
Synonyms	1,1,1-Trifluoro-3-(phenylthio)acetone; 3-(Phenylthio)-1,1,1-trifluoro-2-propanone; 1,1,1-Trifluoro-3-(phenylsulfanyl)acetone; 3-(Phenylsulfanyl)-1,1,1-trifluoroacetone; Phenyl 3,3,3-trifluoro-2-oxopropyl sulfide; α-(Phenylthio)-α,α,α-trifluoroacetone; 3,3,3-Trifluoro-1-(phenylthio)acetone; TFPA-SPh
EINECS	Contact for details

Quality Control

Every batch of 2-Propanone, 1,1,1-Trifluoro-3-(Phenylthio)- is produced and tested under a strict quality management system. We employ advanced analytical techniques including GC, HPLC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.