Description

Tirandamycin is a potent, naturally occurring antibiotic belonging to the tirandamycin class of compounds. Its primary value lies in its significant antibacterial activity, particularly against Gram-positive bacteria, making it a crucial compound for research into novel antimicrobial agents and resistance mechanisms. This product is essential for pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on developing new therapeutic leads and studying bacterial inhibition.

Application

• Antibacterial Research & Development: A key reference standard and active pharmaceutical ingredient (API) intermediate in the discovery of new antibiotics targeting resistant bacterial strains.
• Biochemical Studies: Used as a molecular tool to investigate bacterial RNA polymerase inhibition and other specific mechanisms of antimicrobial action.
• Pharmaceutical Synthesis: Serves as a critical building block or precursor in the semi-synthesis of more complex or potent antimicrobial derivatives.
• Microbiology & Assay Development: Employed as a positive control in high-throughput screening assays to evaluate the efficacy of new compounds against specific pathogens.
• Academic Research: Utilized in university and institutional labs for studies related to natural product chemistry, biosynthesis, and structure-activity relationships (SAR).

Basic Information

Product Name	Tirandamycin
CAS No.	34429-70-4
Molecular Formula	C23H31NO7
Molecular Weight	433.50 g/mol
Synonyms	Tirandamycin A; Tirandamycin; Antibiotic U-58,431; U-58,431; Tirandamycic acid; (2E,4E,6E,8E)-10-[(2S,3S,4S,5S,6R)-4,5-Dihydroxy-3,6-dimethyloxan-2-yl]-3,5,7,9-tetramethyldeca-2,4,6,8-tetraenoic acid; Streptomyces tirandis metabolite
EINECS	Contact for details

Quality Control

Our Tirandamycin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods for structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, purity, and other critical parameters is provided with every shipment to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.