Description

Methyl 3-Bromo-2-oxobutanoate is a versatile brominated ketoester building block, essential for advanced organic synthesis. Its reactive bromine and carbonyl groups make it a critical intermediate for constructing complex molecular architectures with high precision. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing heterocyclic or α-keto acid motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions to introduce functionalized side chains.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialized polymers and advanced organic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of enzyme inhibitors or activity-based probes for biochemical research.

Basic Information

Product Name	Methyl 3-Bromo-2-oxobutanoate
CAS No.	34329-73-2
Molecular Formula	C5H7BrO3
Molecular Weight	195.01 g/mol
Synonyms	Methyl 3-bromo-2-oxobutyrate; 3-Bromo-2-oxobutanoic acid methyl ester; Methyl α-bromoacetoacetate; 2-Oxo-3-bromobutanoic acid methyl ester; 3-Bromoacetoacetic acid methyl ester; Bromoacetoacetic acid methyl ester; Methyl 3-bromoacetoacetate
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromo-2-oxobutanoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and GC-MS, NMR, and IR for structural confirmation, to ensure it meets the stringent requirements of research and development. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.