Description

(2S)-2α-Phenylcyclohexanone is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry makes it a critical precursor for the development of enantiomerically pure pharmaceuticals and specialty chemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality chiral synthons for complex molecule construction.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) agents and other therapeutic compounds requiring specific stereochemistry.
• Asymmetric Synthesis: Serves as a versatile starting material or chiral auxiliary in catalytic asymmetric reactions to construct complex molecular architectures.
• Agrochemical Research: Used in the development of novel, enantiomerically pure pesticides and herbicides where biological activity is stereospecific.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, fragrances, and advanced materials that rely on chiral purity.
• Academic & R&D: A valuable compound for methodological development in organic chemistry laboratories and for investigating new synthetic pathways.

Basic Information

Product Name	(2S)-2α-Phenylcyclohexanone
CAS No.	34281-94-2
Molecular Formula	C12H14O
Molecular Weight	174.24 g/mol
Synonyms	(2S)-2-Phenylcyclohexanone; (S)-2-Phenylcyclohexanone; (-)-2-Phenylcyclohexanone; L-2-Phenylcyclohexanone; (S)-(-)-2-Phenylcyclohexanone; 2-Phenylcyclohexanone, (S)-; Cyclohexanone, 2-phenyl-, (2S)-
EINECS	Contact for details

Quality Control

Our (2S)-2α-Phenylcyclohexanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chiral purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR, and GC/HPLC for chemical purity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.