Description

2-Bromo-4-T-Butyl-1-Fluorobenzene is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and a bulky tert-butyl group, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions to introduce the aryl moiety.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine and bromine atoms contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized phosphine or N-heterocyclic carbene (NHC) ligands used in asymmetric catalysis.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and polymers where the tert-butyl group improves solubility and processability.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	2-Bromo-4-T-Butyl-1-Fluorobenzene
CAS No.	34252-94-3
Molecular Formula	C10H12BrF
Molecular Weight	231.11 g/mol
Synonyms	1-Bromo-3-tert-butyl-4-fluorobenzene; 2-Bromo-4-tert-butylfluorobenzene; 4-tert-Butyl-2-bromo-1-fluorobenzene; 3-tert-Butyl-4-fluorobromobenzene; 2-Bromo-4-(1,1-dimethylethyl)-1-fluorobenzene; 4-(tert-Butyl)-2-bromofluorobenzene; 2-Bromo-4-tert-butyl-1-fluorobenzene; 34252-94-3
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-T-Butyl-1-Fluorobenzene is manufactured and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to ensure the material meets your precise research and development requirements. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥98.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.