Description

(3Ar,4R,5E,11As)-4-Acetoxy-3A,7,8,10,11,11A-Hexahydro-6-Methyl-3,10-Bis(Methylene)Cyclodeca[B]Furan-2,9(3H,4H)-Dione is a complex sesquiterpene lactone derivative with a unique fused ring structure. This compound serves as a high-value synthetic intermediate and a scaffold for advanced chemical synthesis, prized for its intricate stereochemistry and functional groups. It is primarily required by pharmaceutical research and fine chemical synthesis teams for developing novel active ingredients and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex natural product analogs and potential drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis.
• Organic Synthesis: Serves as a sophisticated starting material or intermediate for synthesizing other sesquiterpenoids and complex molecules.
• Academic & Institutional Research: Utilized in chemical biology and synthetic methodology development due to its challenging stereogenic centers.
• Reference Standard: Acts as an analytical standard for quality control and identification in related chemical processes.

Basic Information

Product Name	(3Ar,4R,5E,11As)-4-Acetoxy-3A,7,8,10,11,11A-Hexahydro-6-Methyl-3,10-Bis(Methylene)Cyclodeca[B]Furan-2,9(3H,4H)-Dione
CAS No.	34226-88-5
Molecular Formula	C17H18O5
Molecular Weight	302.32 g/mol
Synonyms	4-Acetoxy-3A,7,8,10,11,11A-hexahydro-6-methyl-3,10-bis(methylene)cyclodeca[b]furan-2,9-dione; 4-Acetoxy-6-methyl-3,10-bis(methylene)cyclodeca[b]furan-2,9-dione; Parthenolide 4-acetate derivative; Germacranolide sesquiterpene lactone acetate; 34226-88-5; Cyclodeca[b]furan-2,9-dione, 4-(acetyloxy)-3a,7,8,10,11,11a-hexahydro-6-methyl-3,10-bis(methylene)-, (3aR,4R,5E,11aS)-
EINECS	Contact for details

Quality Control

Our (3Ar,4R,5E,11As)-4-Acetoxy-3A,7,8,10,11,11A-Hexahydro-6-Methyl-3,10-Bis(Methylene)Cyclodeca[B]Furan-2,9(3H,4H)-Dione is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.