Description

(2S,4Bα,8Aβ)-Tetradecahydro-2β-Hydroxy-4Aβ,8-Dimethyl-2-Isopropyl-1-Oxo-3β,10Aβ-Epoxyphenanthrene-8β-Carboxylic Acid Methyl Ester CAS NO 34226-18-1 is a high-purity, complex diterpenoid derivative with a defined stereochemistry. This compound serves as a critical advanced intermediate in the synthesis of complex natural products and novel pharmaceutical agents. It is primarily required by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing new therapeutic compounds and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex diterpenoid-based drug candidates and active pharmaceutical ingredients (APIs).
• Organic Synthesis Research: Valuable chiral precursor for academic and industrial research in stereoselective synthesis and methodology development.
• Natural Product Synthesis: Used in the total or semi-synthesis of complex natural products with potential biological activity.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals for agrochemicals or material science applications.

Basic Information

Product Name	(2S,4Bα,8Aβ)-Tetradecahydro-2β-Hydroxy-4Aβ,8-Dimethyl-2-Isopropyl-1-Oxo-3β,10Aβ-Epoxyphenanthrene-8β-Carboxylic Acid Methyl Ester
CAS No.	34226-18-1
Molecular Formula	C23H36O5
Molecular Weight	392.53 g/mol
Synonyms	Methyl (2S,4aR,4bS,8aS,10aR)-2-hydroxy-2-isopropyl-4b,8a-dimethyl-3,4,4a,4b,5,6,7,8,8a,9,10,10a-dodecahydro-1-oxophenanthrene-4a-carboxylate; Methyl 2-hydroxy-2-isopropyl-4b,8a-dimethyl-3,4,4a,4b,5,6,7,8,8a,9,10,10a-dodecahydro-1-oxophenanthrene-4a-carboxylate; Diterpenoid Methyl Ester Intermediate; 34226-18-1; 8β-Carbomethoxy-14-hydroxy-13-isopropylpodocarpa-8,11,13-trien-7-one (related structural descriptor)
EINECS	Contact for details

Quality Control

Our (2S,4Bα,8Aβ)-Tetradecahydro-2β-Hydroxy-4Aβ,8-Dimethyl-2-Isopropyl-1-Oxo-3β,10Aβ-Epoxyphenanthrene-8β-Carboxylic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with research and cGMP-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.