Description

2,2',5,5'-Tetrahydroxy-4,4'-Bis[(2E,6E,10E)-3,7,11,15-Tetramethyl-2,6,10,14-Hexadecatetrenyl]-1,1'-Bi-[1,4-Cyclohexadiene]-3,3',6,6'-Tetrone is a complex, high-value polyprenylated quinone derivative with significant biological activity. This compound is critical for advanced research and development in life sciences due to its potent antioxidant and potential therapeutic properties. It is primarily sought after by pharmaceutical R&D teams, nutraceutical formulators, and academic researchers focusing on natural product chemistry and drug discovery.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate for investigating novel therapeutics, particularly in oncology and neurodegenerative disease models.
• Nutraceutical & Dietary Supplement Formulation: Used as a high-potency bioactive ingredient in premium antioxidant and anti-aging supplement formulations, leveraging its natural origin and strong free radical scavenging activity.
• Biochemical & Life Science Research: Essential for in-vitro and in-vivo studies to elucidate mechanisms of action related to oxidative stress, cell signaling pathways, and enzyme inhibition.
• Natural Product Chemistry & Synthesis: Acts as a challenging synthetic target and a building block for the semi-synthesis of complex natural analogs for structure-activity relationship (SAR) studies.
• Cosmeceutical Development: Incorporated into advanced skincare products for its potential protective effects against environmental skin damage and to promote skin health.

Basic Information

Product Name	2,2',5,5'-Tetrahydroxy-4,4'-Bis[(2E,6E,10E)-3,7,11,15-Tetramethyl-2,6,10,14-Hexadecatetrenyl]-1,1'-Bi-[1,4-Cyclohexadiene]-3,3',6,6'-Tetrone
CAS No.	34198-85-1
Molecular Formula	C50H66O8
Molecular Weight	795.06 g/mol
Synonyms	Garcinol; Camboginol; Brindon; Garcinia indica extract; HCA; Hydroxycitric acid tetrahydroxy derivative; Polyisoprenylated benzophenone; 1,1,2,3-Tetrahydroxy-9H-xanthen-9-one derivative; Kokum butter extract principle
EINECS	Contact for details

Quality Control

Every batch of Garcinol is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for your research and production needs. A detailed Certificate of Analysis (COA) including results for HPLC purity, heavy metals, residual solvents, and microbiological limits is supplied with each shipment. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates and rigorous research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. For short-term use, storage at controlled room temperature (15-25°C) is acceptable. The container should be kept in a desiccated environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	Yellow to orange amorphous powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines
Total Aerobic Microbial Count	≤ 1000 CFU/g
Total Yeast & Mold Count	≤ 100 CFU/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.