Description

(2S,3R)-1-O,2-Seco-1,3,15-Trideoxy-2,3-Epoxypodolactone B is a specialized, high-purity chemical intermediate derived from podolactone, characterized by its unique stereochemistry and epoxide functionality. This compound matters for its role as a critical building block in the synthesis of complex natural product analogs and novel pharmaceutical candidates, offering precise structural control. It is primarily needed by research institutions and pharmaceutical development companies focused on oncology, anti-inflammatory, and other therapeutic areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the research and development of novel drug candidates, particularly in oncology and anti-inflammatory therapeutic areas.
• Organic Synthesis Building Block: Utilized in advanced organic chemistry for constructing complex molecular architectures, leveraging its reactive epoxide and lactone moieties.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize biological activity of podolactone-derived compounds.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and compound identification.
• Biochemical Research: Applied in studies investigating biological pathways and mechanisms where natural product-like molecules are used as probes.

Basic Information

Product Name	(2S,3R)-1-O,2-Seco-1,3,15-Trideoxy-2,3-Epoxypodolactone B
CAS No.	34198-79-3
Molecular Formula	C20H28O5
Molecular Weight	348.44 g/mol
Synonyms	1-O,2-Seco-1,3,15-trideoxy-2,3-epoxypodolactone B; (2S,3R)-Podolactone derivative; 2,3-Epoxypodolactone B seco-derivative; NSC 341983; Podolactone epoxide intermediate; (2S,3R)-1-O,2-Seco-trideoxyepoxypodolactone B
EINECS	Contact for details

Quality Control

Our (2S,3R)-1-O,2-Seco-1,3,15-Trideoxy-2,3-Epoxypodolactone B is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.