Description

Glycyrrhetic Acid 3-o-Glucuronide is a key bioactive metabolite derived from glycyrrhizin, the primary sweet-tasting constituent of licorice root. This compound is valued for its potent biological activity, particularly its targeted anti-inflammatory and skin-whitening effects, which are often more pronounced than its precursor. It serves as a critical high-purity reference standard and active ingredient for manufacturers in the pharmaceutical, cosmetic, and nutraceutical industries seeking advanced, research-backed formulations.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and quantification of licorice-derived compounds in drug formulations and herbal extracts.
• Cosmetic Actives: Incorporated into premium skincare products for its efficacy in inhibiting tyrosinase activity (skin brightening) and reducing inflammation associated with conditions like acne and eczema.
• Nutraceutical Research: Serves as a key ingredient in advanced dietary supplement research focused on hepatoprotective (liver-protecting) and anti-ulcer activities.
• Biochemical Research: Utilized in in-vitro and in-vivo studies to investigate specific metabolic pathways, receptor interactions, and the mechanisms of triterpenoid bioactivity.
• Natural Product Isolation & Analysis: Essential for the calibration of analytical equipment (HPLC, LC-MS) in laboratories specializing in the isolation and characterization of plant metabolites.

Basic Information

Product Name	Glycyrrhetic Acid 3-o-Glucuronide
CAS No.	34096-83-8
Molecular Formula	C36H54O11
Molecular Weight	662.81 g/mol
Synonyms	Glycyrrhetinic Acid 3-O-Glucuronide; 3β-[(O-β-D-Glucopyranuronosyl)oxy]-11-oxoolean-12-en-30-oic Acid; Enoxolone Glucuronide; Glycyrrhetate Glucuronide; 3-O-β-D-Glucuronosyl-glycyrrhetic Acid; GA3G; Licorice Saponin Metabolite G
EINECS	Contact for details

Quality Control

Our Glycyrrhetic Acid 3-o-Glucuronide is produced and tested under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and formulation. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We can supply material compliant with the standards required for use as a pharmaceutical reference compound.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.