Description

Lankamycin 15-Acetate is a chemically modified derivative of the macrolide antibiotic lankamycin, characterized by the acetylation at the 15-position. This modification is significant for altering the compound's biological activity, solubility, and pharmacokinetic properties, making it a valuable intermediate in pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for the synthesis of novel antibiotic agents and for structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel macrolide antibiotics and semi-synthetic derivatives.
• Biochemical Research: Used as a reference standard or probe in studies investigating bacterial protein synthesis inhibition and antibiotic resistance mechanisms.
• Structure-Activity Relationship (SAR) Studies: Essential for modifying the lankamycin core structure to explore and enhance antimicrobial potency, spectrum, and safety profiles.
• Antimicrobial Agent Development: Serves as a precursor in the development of new therapeutic agents targeting Gram-positive and atypical pathogens.

Basic Information

Product Name	Lankamycin 15-Acetate
CAS No.	33956-59-1
Molecular Formula	C39H65NO13
Molecular Weight	755.94 g/mol
Synonyms	15-O-Acetyllankamycin; Lankamycin acetate; Antibiotic LA-7017 acetate; 4''-O-Acetyllankamycin; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-7-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-4,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione 15-acetate
EINECS	Contact for details

Quality Control

Our Lankamycin 15-Acetate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.