Description

2,2,2-Trifluoroacetaldehyde Hydrate is a versatile fluorinated building block essential for introducing the trifluoromethyl group into complex molecular architectures. Its primary value lies in enabling the synthesis of high-value fluorinated compounds, which are critical for enhancing the metabolic stability, lipophilicity, and bioavailability of target molecules. This chemical is particularly sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the production of fluorinated active pharmaceutical ingredients (APIs), including antiviral and anticancer agents.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting technologies.
• Fluorinated Polymer Modifier: Imparts unique chemical resistance and surface properties to specialty polymers and coatings.
• Organic Synthesis Reagent: Employed in nucleophilic addition reactions and as a precursor for other trifluoromethyl-containing reagents.
• Fluorine-19 NMR Spectroscopy: Can be used as a reference compound or a tagging agent in analytical chemistry.

Basic Information

Product Name	2,2,2-Trifluoroacetaldehyde Hydrate
CAS No.	33953-86-5
Molecular Formula	C2H3F3O2
Molecular Weight	116.04 g/mol
Synonyms	Trifluoroacetaldehyde Monohydrate; 2,2,2-Trifluoroethanal Hydrate; Trifluoroacetic Aldehyde Hydrate; Glycolic Aldehyde Trifluoromethyl Hydrate; TFAH; CF3CHO·H2O; 1,1,1-Trifluoro-2-hydroxyethane; 2,2,2-Trifluoro-1-hydroxyethane
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoroacetaldehyde Hydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.