Description

(1R)-1,2,3,4,4A,4Bβ,5,6,7,8,10,10Aα-Dodecahydro-1,4Aβ-Dimethyl-7β-(1-Methylethyl)-1α-Phenanthrenecarboxylic Acid Methyl Ester is a high-purity, sterically defined diterpenoid derivative. This compound serves as a critical advanced intermediate or reference standard in complex organic synthesis and pharmaceutical research. It is essential for R&D chemists and process development scientists working in pharmaceuticals, agrochemicals, and fine chemical sectors who require structurally precise building blocks for novel active ingredient development.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of complex natural product analogs and novel therapeutic agents.
• Reference Standard: Used in analytical method development and quality control for purity and identity verification in research and manufacturing.
• Organic Synthesis Building Block: Employed in medicinal chemistry for constructing sterically hindered, polycyclic frameworks due to its defined stereochemistry.
• Agrochemical Research: Serves as a starting material for developing new plant growth regulators or pesticides with specific stereochemical requirements.
• Academic & Institutional Research: Utilized in universities and research institutes for studies in synthetic methodology, catalysis, and structure-activity relationships (SAR).
• Process Chemistry Development: Acts as a model compound for scaling up stereoselective synthesis and optimizing reaction conditions.

Basic Information

Product Name	(1R)-1,2,3,4,4A,4Bβ,5,6,7,8,10,10Aα-Dodecahydro-1,4Aβ-Dimethyl-7β-(1-Methylethyl)-1α-Phenanthrenecarboxylic Acid Methyl Ester
CAS No.	33892-13-6
Molecular Formula	C21H34O2
Molecular Weight	318.50 g/mol
Synonyms	Methyl (1R,4aS,4bR,7S,10aS)-1,4a-dimethyl-7-(propan-2-yl)-1,2,3,4,4a,4b,5,6,7,8,10,10a-dodecahydrophenanthrene-1-carboxylate; Abietic Acid Methyl Ester Derivative; Diterpene Methyl Ester; (1R)-Dehydroabietic Acid Methyl Ester; 1-Phenanthrenecarboxylic Acid, 1,2,3,4,4a,4b,5,6,7,8,10,10a-dodecahydro-1,4a-dimethyl-7-(1-methylethyl)-, methyl ester, (1R,4aS,4bR,7S,10aS)-; Methyl Dehydroabietate (specified stereoisomer)
EINECS	Contact for details

Quality Control

Our (1R)-1,2,3,4,4A,4Bβ,5,6,7,8,10,10Aα-Dodecahydro-1,4Aβ-Dimethyl-7β-(1-Methylethyl)-1α-Phenanthrenecarboxylic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure identity, strength, and purity. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.