Description

(S)-4,7A-Dimethyl-2,3,7,7A-Tetrahydro-6H-Indene-1,5-Dione is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry and functionalized indane-dione structure make it a valuable building block for creating complex, optically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced, stereospecific pesticides and herbicides.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development of new catalytic systems.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals requiring specific stereochemistry.
• Academic & Industrial R&D: A critical reagent for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	(S)-4,7A-Dimethyl-2,3,7,7A-Tetrahydro-6H-Indene-1,5-Dione
CAS No.	33878-96-5
Molecular Formula	C11H14O2
Molecular Weight	178.23 g/mol
Synonyms	(4S,7aS)-4,7a-Dimethyl-2,3,7,7a-tetrahydro-1H-indene-1,5(4H,6H)-dione; (S)-4,7a-Dimethyl-2,3,7,7a-tetrahydro-1H-indene-1,5(4H,6H)-dione; (S)-4,7a-Dimethyl-2,3,7,7a-tetrahydro-6H-indene-1,5-dione; (S)-Perhydro-4,7a-dimethyl-1,5-indanedione; (S)-Hexahydro-4,7a-dimethyl-1H-indene-1,5(4H)-dione; (S)-4,7a-Dimethylhexahydro-1H-indene-1,5(4H)-dione; (S)-4,7a-Dimethylperhydroindane-1,5-dione
EINECS	Contact for details

Quality Control

Our (S)-4,7A-Dimethyl-2,3,7,7A-Tetrahydro-6H-Indene-1,5-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis (HPLC, Chiral GC), to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.