Description

(1Ar)-1Aβ,2A,4Aβ,4Bβ,6,8,9B,9Cβ-Octahydro-2β-Hydroxy-2Aβ,9Bα-Dimethyl-6β-Isopropyl-2H,3H-Furo[2',3',4':4,5]Oxireno[7,8]Naphtho[2,1-C]Pyran-3,8-Dione is a complex, high-purity diterpenoid derivative with a fused polycyclic structure, serving as a critical advanced intermediate for pharmaceutical research and synthesis. Its intricate oxireno-naphthopyranone framework makes it a valuable scaffold for developing novel bioactive compounds, particularly in oncology and anti-inflammatory therapeutic areas. This compound is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of complex natural product analogs and new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel diterpenoid-based drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Natural Product Synthesis: Serves as an advanced intermediate in the total or semi-synthesis of complex natural products with biological activity.
• Biochemical Research: Employed in studies investigating enzyme inhibition and receptor binding mechanisms due to its specific stereochemistry.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Fine Chemical Synthesis: Intermediate for creating specialized flavors, fragrances, and other high-value fine chemicals requiring complex stereocenters.

Basic Information

Product Name	(1Ar)-1Aβ,2A,4Aβ,4Bβ,6,8,9B,9Cβ-Octahydro-2β-Hydroxy-2Aβ,9Bα-Dimethyl-6β-Isopropyl-2H,3H-Furo[2',3',4':4,5]Oxireno[7,8]Naphtho[2,1-C]Pyran-3,8-Dione
CAS No.	33722-77-9
Molecular Formula	C22H28O6
Molecular Weight	388.46 g/mol
Synonyms	Furo[2',3',4':4,5]oxireno[7,8]naphtho[2,1-c]pyran-3,8-dione, octahydro derivative; 2H,3H-Furo[2',3',4':4,5]oxireno[7,8]naphtho[2,1-c]pyran-3,8-dione, 1a,2,4a,4b,6,8,9b,9c-octahydro-2-hydroxy-2,9b-dimethyl-6-(1-methylethyl)-, (1aR,2S,4aR,4bR,6R,8S,9bR,9cR)-; Abietic acid derivative; Diterpenoid oxirene; Advanced abietane intermediate
EINECS	Contact for details

Quality Control

Our (1Ar)-1Aβ,2A,4Aβ,4Bβ,6,8,9B,9Cβ-Octahydro-2β-Hydroxy-2Aβ,9Bα-Dimethyl-6β-Isopropyl-2H,3H-Furo[2',3',4':4,5]Oxireno[7,8]Naphtho[2,1-C]Pyran-3,8-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be light-sensitive and should be handled under inert atmosphere for long-term storage to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.