Description

1-Bromo-8-Fluoronaphthalene is a high-purity halogenated naphthalene derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, provides distinct reactivity and electronic properties for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated naphthalene cores.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides where the fluoronaphthalene moiety enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a building block for organic electronic materials, including charge-transport layers and emissive materials in display technologies.
• Organic Ligand Preparation: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and functional group transformations in academic and industrial R&D.
• Dye & Pigment Intermediate: Used in the production of specialized dyes and pigments where halogenation tunes color properties and lightfastness.

Basic Information

Product Name	1-Bromo-8-Fluoronaphthalene
CAS No.	33718-15-9
Molecular Formula	C₁₀H₆BrF
Molecular Weight	225.06 g/mol
Synonyms	8-Fluoro-1-bromonaphthalene; 1-Bromo-8-fluoronaphthalene; Naphthalene, 1-bromo-8-fluoro-; 8-Fluoronaphthalen-1-yl bromide
EINECS	Contact for details

Quality Control

Our 1-Bromo-8-Fluoronaphthalene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and inert atmosphere. Handle and store under an inert gas (nitrogen/argon) for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.