Description

3-Butynal Dimethyl Acetal is a versatile alkyne-protected aldehyde building block, essential for advanced organic synthesis. Its unique structure, featuring both an acetal-protected carbonyl and a terminal alkyne, makes it a critical intermediate for constructing complex molecular architectures with high precision. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring alkyne or protected aldehyde functionalities for click chemistry or further derivatization.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators that incorporate acetylene-based molecular scaffolds.
• Material Science Research: Serves as a monomer or precursor for synthesizing specialized polymers, dendrimers, and organic electronic materials with tailored properties.
• Chemical Biology Probes: Employed in the creation of molecular probes and bioconjugation reagents, leveraging the alkyne group for bioorthogonal labeling strategies.
• Cross-Coupling Reactions: A valuable substrate in Sonogashira, Glaser, and other palladium-catalyzed cross-coupling reactions to form complex carbon-carbon bonds.
• Fine Chemical Production: Intermediate in the multi-step synthesis of flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	3-Butynal Dimethyl Acetal
CAS No.	33639-45-1
Molecular Formula	C6H10O2
Molecular Weight	114.14 g/mol
Synonyms	3-Butynal Dimethyl Acetal; 3-Butyn-1-al Dimethyl Acetal; 1,1-Dimethoxy-3-butyn-1-ol; 3-Butyn-1-aldehyde Dimethyl Acetal; 1,1-Dimethoxy-3-butyne; 3-Butynal DMA; 3-Butyn-1-aldehyde DMA; 3-Butynylaldehyde Dimethyl Acetal
EINECS	Contact for details

Quality Control

Our 3-Butynal Dimethyl Acetal is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. The compound is moisture-sensitive; ensure containers are kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.