Description

1,3-Dimethoxy-2-(Methylthio)Benzene is a specialized aromatic ether and thioether compound with the CAS registry number 33617-67-3. This chemical serves as a versatile and valuable intermediate in advanced organic synthesis, prized for its unique substitution pattern that allows for selective functionalization. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those with complex heterocyclic or substituted benzene cores.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where its methoxy and methylthio groups act as directing or functional handles.
• Organic Synthesis Reagent: Employed in academic and industrial R&D labs for palladium-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, due to its halogen-substituted derivatives.
• Material Science Precursor: Acts as a monomer or starting material in the development of specialty polymers, liquid crystals, or organic electronic materials.
• Flavor & Fragrance Industry: Serves as a potential intermediate for synthesizing specific aroma chemicals, leveraging its dimethoxybenzene structure.

Basic Information

Product Name	1,3-Dimethoxy-2-(Methylthio)Benzene
CAS No.	33617-67-3
Molecular Formula	C9H12O2S
Molecular Weight	184.26 g/mol
Synonyms	2-(Methylthio)-1,3-dimethoxybenzene; 1,3-Dimethoxy-2-methylthiobenzene; Benzene, 1,3-dimethoxy-2-(methylthio)-; 2-Methylthio-1,3-dimethoxybenzene; 1,3-Dimethoxy-2-(methylsulfanyl)benzene; 2-(Methylsulfanyl)-1,3-dimethoxybenzene; NSC 403107
EINECS	Contact for details

Quality Control

Every batch of 1,3-Dimethoxy-2-(Methylthio)Benzene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) specifying identity, purity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.