Description

2-(Tetrahydrofuran-2-Yl)Acetonitrile is a versatile nitrile-functionalized heterocyclic building block, crucial for advanced organic synthesis. Its unique structure, combining a tetrahydrofuran ring with an acetonitrile moiety, makes it a valuable precursor for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediates: Key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing fused heterocyclic systems.
• Agrochemical Synthesis: Used as a building block in the development of new herbicides, fungicides, and insecticides with specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Flavor and Fragrance Chemistry: Acts as an intermediate for the synthesis of complex odorants and flavoring agents.

Basic Information

Product Name	2-(Tetrahydrofuran-2-Yl)Acetonitrile
CAS No.	33414-62-9
Molecular Formula	C6H9NO
Molecular Weight	111.14 g/mol
Synonyms	2-(Oxolan-2-yl)acetonitrile; (Tetrahydro-2-furanyl)acetonitrile; 2-(Tetrahydro-2-furanyl)acetonitrile; 2-(2-Furanyl)acetonitrile, tetrahydro-; THF-2-Acetonitrile; 2-(Oxolanyl)acetonitrile; α-(Tetrahydro-2-furyl)acetonitrile
EINECS	Contact for details

Quality Control

Our 2-(Tetrahydrofuran-2-Yl)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The product is moisture-sensitive; ensure containers are kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.4400 - 1.4450
Density (20°C)	1.00 - 1.05 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.